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CBS selectively replenishes the GSH levels under cystine-restricted conditions Multiple critical enzymes are involved in the normal function of the TSS pathway, including CBS and CSE, which catalyze the first two steps of de novo cysteine generation, from homocysteine to cystathionine and then cysteine

A study involving 50 obese children aged 4 to 18 years, along with 20 control subjects, reported significantly higher serum TMAO levels in the obese group compared to controls

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Clinical Nutrition, 39(2), 387-401

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